Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy

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Sildenafil citrate use and the incidence of nonarteritic anterior ischemic optic neuropathy

Nonarteritic anterior ischemic optic neuropathy (NAION) has been reported rarely in men after taking sildenafil or other phosphodiesterase 5 inhibitors for erectile dysfunction (ED). The incidence of NAION in men receiving sildenafil treatment for ED was estimated using pooled safety data from global clinical trials and European observational studies. Based on clinical trial data in more than 1...

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Surgery for nonarteritic anterior ischemic optic neuropathy.

BACKGROUND Nonarteritic ischemic optic neuropathy is characterized by sudden and painless loss of vision in one eye, accompanied by pallid swelling of the optic disc. Although various medical interventions, such as corticosteroids and phenytoin sodium, have been used to treat nonarteritic ischemic optic neuropathy, no therapy has been proven effective. OBJECTIVES The objective of this review ...

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Incipient nonarteritic anterior ischemic optic neuropathy.

OBJECTIVE To describe the clinical entity of incipient nonarteritic anterior ischemic optic neuropathy (NAION). DESIGN Cohort study. PARTICIPANTS Fifty-four patients (60 eyes) seen in our clinic from 1973 through 2000. METHODS At their first visit to our clinic, all patients gave a detailed ophthalmic and medical history and underwent a comprehensive ophthalmic evaluation, color fundus ph...

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Nonarteritic ischemic optic neuropathy.

BACKGROUND To describe the systemic and visual characteristics and prognosis in patients with nonarteritic ischemicoptic neuropathy (NAION) undergoing different treatments. METHODS Retrospective chart review was performed in Kaohsiung Veterans General Hospital patients from 1995-2005 with a clinical diagnosis of NAION, including nonarteritic anterior ischemic optic neuropathy and posterior is...

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Bilateral Simultaneous Nonarteritic Anterior Ischemic Optic Neuropathy after Ingestion of Sildenafil for Erectile Dysfunction

Purpose. To describe a patient who developed bilateral, simultaneous nonarteritic anterior ischemic optic neuropathy (NAION) after ingestion of Sildenafil citrate (Viagra) for erectile dysfunction. Methods. Observational case report. Results. A 60-year-old diabetic man noted sudden decrease of vision in both eyes 16 hours after his third consecutive 50 mg daily Sildenafil ingestion. A diagnosis...

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ژورنال

عنوان ژورنال: International Journal of Clinical Practice

سال: 2006

ISSN: 1368-5031

DOI: 10.1111/j.1368-5031.2006.00904.x